Cynobacteria is usually encouraged with the presence of nitrate and ammonia, which are both fixed forms of nitrogen. Chemi-clean helps clean and remove this problem algae through its own unique process. Most other red slime removers use purely antibiotics, namely erythromycin to take care of the algae. The use of such substances with in your aquarium can have disastrous effects upon your nitrifying bacteria and cause your tank to crash, killing the inhabitants of your aquarium.The use of chemi-clean not only as a problem solver, when red slime is present, but as a regular maintenance procedure will help keep your water crystal clear and your tank free of unwanted cynobacteria.For best results, turn off UV sterilizer or Ozonizer and Protein Skimmer. Remove Chemi-Pure or Carbon Filtration for 24 hours following each treatment.It is advisable to do at least a 20% water change after full treatment.You must use an air stone when using Chemi-Clean. Place airstone in the aquarium prior to and during treatment.* Removes disease causing red cyanobacteria (red slime) from live coral.* Removes red slime, black, blue-green and bubble producing algae.* Oxidizes trapped organic sludge and sediment.* Clarifies aquarium water to crystal clear.* Promotes ideal enzyme balance.* Contains no phosphates, algaecides or erythromycin succinate.* Safe for reef tanks, all invertebrates, desirable macro algaes, nitrifying bacteria and fish.* Treats up to 300 Gallons.